Age-standard qualities off 86,149 women in the latest NHS I inside the 1994 and you can 94,715 feamales in brand new NHS II for the 1995 of the quintiles of magnesium, potassium, and you can calcium supplements consumption step one
Design 2 is actually modified as for design step 1 and intakes off potassium and you may calcium supplements (quintiles regarding grams/d)
In the multivariate analyses, full and you will dieting magnesium intakes was indeed inversely of the likelihood of overall however, ischemic otherwise hemorrhagic stroke ( Table dos). The new pooled multivariate RR for total stroke is actually 0.87 (95% CI: 0.78, 0.97; P-development = 0.07) to your assessment of women regarding the higher which have lowest quintiles of total magnesium consumption; while the fresh new pooled multivariate RR towards the analysis away from higher that have reduced quintiles out of dietary magnesium consumption was 0.81 (95% CI: 0.69, 0.94; P-pattern = 0.001) to have total coronary arrest. Total potassium consumption try inversely of this threat of overall however, not ischemic otherwise hemorrhagic coronary arrest ( Table 3). To have research of women regarding the highest with lower quintiles of overall potassium intake, the new pooled multivariate RR to own total stroke is actually 0.89 (95% CI: 0.80, 0.99; P-trend = 0.01). Multivariate RRs for both magnesium and you will potassium was indeed attenuated when all of the step three nutrients had been as part of the activities simultaneously (multivariate model 2). There clearly was zero tall association anywhere between full otherwise fat reduction calcium intake and complete, ischemic, otherwise hemorrhagic stroke ( Table 4). Multivariate RRs getting total magnesium (Supplemental Dining table step 1), full potassium (Supplemental Dining table dos), full calcium supplements (Supplemental Desk step three), dietary magnesium (Extra Dining table 4), fat reduction potassium (Extra Desk 5), and you may weight loss calcium supplements (Supplemental Dining table 6) and you can risk of overall, ischemic, and you may hemorrhagic shots each cohort on their own receive throughout the extra issue.
Pooled RRs (95% CIs) regarding total, ischemic, and you will hemorrhagic shots by quintiles of total and you may fat loss magnesium consumption within the 86,149 women in new NHS I and 94,715 ladies in the brand new NHS II step 1
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) out-of overall, ischemic, and you may hemorrhagic strokes from the quintiles out-of full and weight loss magnesium consumption inside the 86,149 feamales in the brand new NHS I and you may 94,715 ladies in new NHS II step one
Values are https://datingranking.net/mexican-dating/ the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.